--- title: Metrum News | Confidence Intervals description: Confidence Intervals | --- [![Metrum research group](https://news.metrumrg.com/hs-fs/hubfs/Metrum%20-April2017/images/logo.png?width=235&height=55&name=logo.png "logo.png")](https://www.metrumrg.com/) [![](https://news.metrumrg.com/hs-fs/hubfs/Metrum%20-April2017/images/footer-logo%20(1).png?width=137&height=33&name=footer-logo%20(1).png "logo.png")](https://www.metrumrg.com/) [Contact](https://info.metrumrg.com/contact) - [About](https://www.metrumrg.com/about/) - [Services](https://www.metrumrg.com/services/) - [Metworx](https://www.metrumrg.com/solution/metworx/) - [Open Science](https://www.metrumrg.com/open-science/) - [Publications](https://www.metrumrg.com/publications/) - [Blog](https://news.metrumrg.com/blog) - [Events](https://www.metrumrg.com/events/) - [Careers](https://www.metrumrg.com/careers/) - [About](https://www.metrumrg.com/about/) - [Services](https://www.metrumrg.com/services/) - [Metworx](https://www.metrumrg.com/solution/metworx/) - [Open Science](https://www.metrumrg.com/open-science/) - [Publications](https://www.metrumrg.com/publications/) - [Blog](https://news.metrumrg.com/blog) - [Events](https://www.metrumrg.com/events/) - [Careers](https://www.metrumrg.com/careers/) Enter Search Item Enter Search Item # News ## [Significance and Directional Inference](https://news.metrumrg.com/blog/significance-and-directional-inference) Posted by [Jim Rogers](https://news.metrumrg.com/blog/author/jim-rogers) on Feb 28, 2020, 10:05:48 AM - [Tweet](https://twitter.com/share) [![](https://news.metrumrg.com/hubfs/Metrum%20-April2017/images/header-image.jpg)](https://news.metrumrg.com/blog/significance-and-directional-inference) *In my [first post in this series](https://news.metrumrg.com/blog/a-significant-tilling-of-the-statistical-soil-the-asa-statement-on-statistical-significance-and-p-values-1), I proposed a “starter kit” for developing a statistical argument. This “starter kit” included considerations related to both the direction of effects (“\[Is\] the association directionally consistent with known mechanistic accounts (e.g. based on enzymology)?”) and the magnitude of effects (“Does the association have a magnitude that is consequential in some practical sense?”). In this post, I argue that “significance language” can play a valuable role in discussing the estimated direction of effects, even if supplementary approaches are needed to address more complex questions about magnitude.* [Read More](https://news.metrumrg.com/blog/significance-and-directional-inference) 2 Comments [Click here to read/write comments](https://news.metrumrg.com/blog/significance-and-directional-inference#comments-listing) Topics: [Scientific Writing](https://news.metrumrg.com/blog/topic/scientific-writing), [Significance](https://news.metrumrg.com/blog/topic/significance), [Confidence Intervals](https://news.metrumrg.com/blog/topic/confidence-intervals), [P-values](https://news.metrumrg.com/blog/topic/p-values) ## [A Significant Tilling of the Statistical Soil: The ASA Statement on Statistical Significance and P-values](https://news.metrumrg.com/blog/a-significant-tilling-of-the-statistical-soil-the-asa-statement-on-statistical-significance-and-p-values-1) Posted by [Jim Rogers](https://news.metrumrg.com/blog/author/jim-rogers) on Feb 7, 2020, 10:01:59 AM - [Tweet](https://twitter.com/share) [![](https://news.metrumrg.com/hubfs/Metrum%20-April2017/images/header-image.jpg)](https://news.metrumrg.com/blog/a-significant-tilling-of-the-statistical-soil-the-asa-statement-on-statistical-significance-and-p-values-1) *This is the first in a series of blog posts that will focus on practical problems of summarizing statistical evidence in the context of biomedical science, using the 2016 ASA statement on p-values and significance as a guide. I hope and expect that these posts will find a readership that does not entirely agree with my views in all of their particulars, and that this readership takes advantage of the blog / combox format to register both their agreements and disagreements. Merely good ideas are insufficient to the task at hand ; a shared understanding has to develop in the community of practice ; my hope here is to provide a forum for discussion for that community.* [Read More](https://news.metrumrg.com/blog/a-significant-tilling-of-the-statistical-soil-the-asa-statement-on-statistical-significance-and-p-values-1) 0 Comments [Click here to read/write comments](https://news.metrumrg.com/blog/a-significant-tilling-of-the-statistical-soil-the-asa-statement-on-statistical-significance-and-p-values-1#comments-listing) Topics: [Statistics](https://news.metrumrg.com/blog/topic/statistics), [Scientific Writing](https://news.metrumrg.com/blog/topic/scientific-writing), [Significance](https://news.metrumrg.com/blog/topic/significance), [Confidence Intervals](https://news.metrumrg.com/blog/topic/confidence-intervals), [P-values](https://news.metrumrg.com/blog/topic/p-values) [All posts](https://news.metrumrg.com/blog/all) ## We love to share! Please take advantage of the content we provide here. Our goal is to help, encourge, and inspire you in your own work! If you have suggestions for blog topics, or would like to co-author a blog post with us, [let us know](https://info.metrumrg.com/contact)! ### Posts by Topic - [Metrum News (38)](https://news.metrumrg.com/blog/topic/metrum-news) - [Employee Spotlight (14)](https://news.metrumrg.com/blog/topic/employee-spotlight) - [Methodology, Tools, and Computation (13)](https://news.metrumrg.com/blog/topic/methodology-tools-and-computation) - [Community Outreach (11)](https://news.metrumrg.com/blog/topic/community-outreach) - [Open Science (11)](https://news.metrumrg.com/blog/topic/open-science) - [Neurodegenerative Diseases (3)](https://news.metrumrg.com/blog/topic/neurodegenerative-diseases) - [Confidence Intervals (2)](https://news.metrumrg.com/blog/topic/confidence-intervals) - [Oncology (2)](https://news.metrumrg.com/blog/topic/oncology) - [P-values (2)](https://news.metrumrg.com/blog/topic/p-values) - [Scientific Writing (2)](https://news.metrumrg.com/blog/topic/scientific-writing) - [Significance (2)](https://news.metrumrg.com/blog/topic/significance) - [AI (1)](https://news.metrumrg.com/blog/topic/ai) - [Alzheimer's (1)](https://news.metrumrg.com/blog/topic/alzheimers) - [Bayesian (1)](https://news.metrumrg.com/blog/topic/bayesian) - [Bone Health (1)](https://news.metrumrg.com/blog/topic/bone-health) - [Breast Cancer (1)](https://news.metrumrg.com/blog/topic/breast-cancer) - [CEO (1)](https://news.metrumrg.com/blog/topic/ceo) - [Infectious Diseases (1)](https://news.metrumrg.com/blog/topic/infectious-diseases) - [Machine Learning (1)](https://news.metrumrg.com/blog/topic/machine-learning) - [Mental Health (1)](https://news.metrumrg.com/blog/topic/mental-health) - [Other (1)](https://news.metrumrg.com/blog/topic/other) - [Pediatrics (1)](https://news.metrumrg.com/blog/topic/pediatrics) - [Rare Disorders (1)](https://news.metrumrg.com/blog/topic/rare-disorders) - [Service (1)](https://news.metrumrg.com/blog/topic/service) - [Statistics (1)](https://news.metrumrg.com/blog/topic/statistics) - [Women's Health (1)](https://news.metrumrg.com/blog/topic/womens-health) see all ### Subscribe to Email Updates ### Recent Posts [![Metrum research group ](https://news.metrumrg.com/hs-fs/hubfs/Metrum%20-April2017/images/footer-logo.png?width=145&height=35&name=footer-logo.png "footer-logo.png")](https://www.metrumrg.com/) [Privacy](https://www.metrumrg.com/privacy-policy/)  |  2020 Metrum Research Group