A new client service, new presentation materials, community service and more!
Not rendering correctly? View this email as a web page here.
Metrum Headlines
Metrum offering new Technology Services to clients
Our team is working with clients to deliver end-to-end solutions that support quantitative decision making. Devin Pastoor, Ph.D., Senior Director of Engineering Services, specializes in bridging the unique characteristics of each client’s IT structure with the needs of the scientific team. This unit broadens the services Metrum is able to offer to our clients, particularly on the infrastructure side. Some examples include:
Providing strategies (design, roll out, and support) to migrate from existing tools (SAS/Tableau) to more modern, open, cloud-based workflows;
Developing decision-support dashboards to promote direct executive engagement;
Building and testing prototype workflows and tools to explore potential solutions to business challenges.
We would be happy to discuss how these services can benefit you and your M&S team!
Metrum honored to be a 2018 Marcum Tech Top 40 Award recipient
The Connecticut Technology Council (CTC) and Marcum LLP announced the 2018 Marcum Tech Top 40, the annual recognition of the fastest growing technology companies in Connecticut. This year’s group of top-ranked companies will be honored at the new ConnectiTECH Awards event at the Connecticut Convention Center on October 3.
This marks the eighth time Metrum Research Group has been chosen as a Marcum Tech Top 40 recipient.
Marc R. Gastonguay, Ph.D., Founder and CEO of Metrum Research Group, commented “All credit for our recognition as a Marcum Tech Top 40 company goes to the incredibly talented, bright, and hard-working employees of Metrum Research Group. This is a particularly meaningful honor for our company as it recognizes the amazing tech companies in our home state of CT, a state where many of our staff were educated, or developed on-the-job experience and skills.”
New features added to mrgsolve
There have been some new features rolled out in the evaluation version of mrgsolve.
We have a new formal code block called $PRED that allows users to write models that don't utilize differential equations and where model predictions can be expressed in closed form. For example, users can use $PRED to code an Emax model that utilizes daily AUC (either simulated in the model or in the input data) to drive the effect. While users have always been able to code models like these in mrgsolve, there is now a formal code block to do this. There are also new, relaxed input data set requirements when coding models with $PRED.
Also new in the development version is a mechanism to allow users to schedule events or interventions from within the model itself, rather than requiring the events to be encoded in the input data set. For example, users might wish to create a discontinuity in the simulation where a modeled parameter changes value at a specific time that may not already be included in the data set. Users can now create events like these from within the model itself. The advantage with this approach is that the state of the model at any given time can be utilized to determine the characteristics of the event (for example, what time in the future should the parameter change value?).
Please read more about $PRED and modeled interventions on themrgsolve blog. We're excited to introduce these features for people to test and use on a provisional basis. Hopefully, this functionality will be ready for release into a version on CRAN in the near future.
Presentations & Publications
Award received at ACCP Annual Meeting
Dr. Marc Gastonguay was awarded the Bristol-Myers Squibb Mentorship in Clinical Pharmacology award at the ACCP annual meeting. In Marc's acceptance speech, he stressed the importance of open science. His notes will be posted on ourwebsitesoon.
Marc also co-chaired the conference session entitled "Methodological & Statistical Considerations in Pediatric & Rare Disease Drug Development: External Control Groups & Dose Selection", along with Gopichand Gottipati, Ph.D.
You can find all of these and more on the Metrum Research Group website.
Metrum News to Note
MRG Promotions
Congratulations to the following well-deserved promotions:
Jonathan French, Sc.D., Fellow
Curtis Johnston, Pharm.D., Senior Scientist II
Dan Polhamus, Ph.D., Principal Scientist I
Jayson Wilbur, Ph.D., Principal Scientist I
Jia Kang, Ph.D., Senior Scientist I
Kyle Baron, Pharm.D., Ph.D., Principal Scientist I
Nathanael Dirks, Pharm.D., Ph.D., Principal Scientist I
Jim Marsan, Senior Director of Resource and Project Management
Danielle Dunn, Senior Accounting Manager
Heidi Seaborg, Resourcing & Contracts Manager
Welcome to the Metrum team!
We're excited to announce these additions to the Metrum team:
Eric Burroughs, M.S. - Principal Scientist II
Shona Kidd - Documentation & Process Manager
Jill Wallace - Client Relationship Coordinator
Devin Pastoor Ph.D. - Senior Director of Engineering Services
Katherine Kay, Ph.D. - Research Scientist
Jessica Krystle Roberts, Ph.D., MSCI - Research Associate I
Michael Heathman, M.S. - Group Leader, Principal Scientist II
To learn more about any of our team, visit our website.
Metrum in the Community: Habitat for Humanity
Employees took part in a community service day in May, working with Habitat for Humanity in the Hartford area. Paint brushes and power tools were used to renovate a house, helping make the dream of homeownership a reality for families living in need. Eleven staff members were able to dedicate the day to volunteer to participate in A Brush with Kindness, a program assisting low-income families.
Metrum in the Community:
MS Walk
Employees and families enjoyed participating in a local MS Walk in September.
Metrum Research Group was also proud to be a local sponsor for the event, helping to raise money and awareness for this disease and those it affects.
It's almost time for ACoP9
Find Metrum at ACoP9:
Stop by our exhibit booth - # 8 & 9 - we'd love to say hello to you!
Check out presentations and posters by MRG employees: Matthew Riggs, Ph.D., James Rogers, Ph.D., Kyle Baron, Ph.D., William Gillespie, Ph.D., Janelle Hajjar, M.S., and Ahmed Elmokadem, Ph.D. We will be releasing all of our presented material post ACoP9 via our website.