Rena J. Eudy-Byrne, Ph.D., presented at the 17th American Pediatrics Healthcare & Infectious Diseases Congress in Vancouver, Canada on June 28, 2018. You can see the presentation here.
HBGDki M3 Gut & Growth Model
To understand and separate effects of nutrition and disease on infant growth, a physiologically-based mathematical model was developed describing fat mass (FM) and fat-free mass (FFM) from birth to 2 years. This app allows a user to simulate individual infant phenotypes and infection events and visualize growth and energy levels over time, relative to healthy (WHO) standards.
Physiological aspects of infant growth that can be explored in the app include:
- macronutrient absorption efficiencies
- deposition of metabolizable energy into FM and FFM
- total energy expenditure
- dynamics of severe bacterial and viral infections
- effects of malnutrition on GI/immune function
- recovery from malnutrition