News

MetrumRG "COOPED UP" Webinar Series to Begin

Posted by Matthew M. Riggs, Ph.D. on May 19, 2020 9:11:58 AM

Metrum Research Group's Cellar Office OPen-EDUcation in Pharmacometrics (“COOPED UP”) webinar series will be kicking off next month! These webinars will feature a range of topics, discussed in vignette formats, to share with our community the same training and development in which our staff routinely engages.

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Topics: Open Science

Showing Stripes and more for Rare Disease Day 2020

Posted by Diane Reynolds on Mar 25, 2020 12:52:33 PM

 

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Topics: Community Outreach

Significance and Directional Inference

Posted by Jim Rogers on Feb 28, 2020 10:05:48 AM

In my first post in this series, I proposed a “starter kit” for developing a statistical argument. This “starter kit” included considerations related to both the direction of effects (“[Is] the association directionally consistent with known mechanistic accounts (e.g. based on enzymology)?”) and the magnitude of effects (“Does the association have a magnitude that is consequential in some practical sense?”). In this post, I argue that “significance language” can play a valuable role in discussing the estimated direction of effects, even if supplementary approaches are needed to address more complex questions about magnitude.

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Topics: Scientific Writing, Significance, Confidence Intervals, P-values

Statistical Significance is a Result, Not a Conclusion

Posted by Jim Rogers on Feb 21, 2020 9:56:53 AM

In my previous post, I proposed a “starter kit” for developing a statistical argument. An essential ingredient in this “starter kit” was the identification of the context of inquiry as being confirmatory, explanatory, or something in between. In this post, I propose several criteria for defining a confirmatory context, and I suggest principles for using the language of “statistical significance” when confirmatory contexts do not obtain.

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MetrumRG Winter 2020 Newsletter

Posted by Diane Reynolds on Feb 12, 2020 11:12:21 AM

 

Read the latest news, events, and publications from Metrum Research Group in our Winter 2020 Newsletter.

Here’s what you will find in our newsletter:  

  • Join MetrumRG at ASCPT: Our workshop, our Booth and an award!
  • New models and blog posts on our website!
  • Announcement about our newest team members!
  • Upcoming events our scientists will be attending or presenting at.
  • Publications and presentations by MetrumRG scientists.
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Topics: Metrum News

A Significant Tilling of the Statistical Soil: The ASA Statement on Statistical Significance and P-values

Posted by Jim Rogers on Feb 7, 2020 10:01:59 AM

This is the first in a series of blog posts that will focus on practical problems of summarizing statistical evidence in the context of biomedical science, using the 2016 ASA statement on p-values and significance as a guide. I hope and expect that these posts will find a readership that does not entirely agree with my views in all of their particulars, and that this readership takes advantage of the blog / combox format to register both their agreements and disagreements. Merely good ideas are insufficient to the task at hand ; a shared understanding has to develop in the community of practice ; my hope here is to provide a forum for discussion for that community.

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Topics: Statistics, Scientific Writing, Significance, Confidence Intervals, P-values

Check out these recent publications by authors at Metrum Research Group and our collaborators!

Posted by Heidi Seaborg on Jan 16, 2020 8:00:00 AM

 

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Topics: Metrum News

MetrumRG Fall Community Outreach Efforts

Posted by Diane Reynolds on Dec 18, 2019 7:30:25 AM

The fall season brought several opportunities for MetrumRG employees to give to local communities.

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Topics: Community Outreach

MetrumRG at ACoP 2019

Posted by Diane Reynolds on Nov 19, 2019 12:58:45 PM

MetrumRG scientists traveled to Orlando, FL to join the American Conference on Pharmacometrics for their 2019 annual meeting in October.

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Topics: Metrum News

MetrumRG Fall 2019 Newsletter

Posted by Heidi Seaborg on Oct 2, 2019 1:28:51 PM

 

Read the latest news, events, and publications from Metrum Research Group in our Fall 2019 Newsletter.

Here’s what you will find in our newsletter:  

  • MetrumRG at ACoP10: Our workshops, presentations, and posters!
  • Announcement about our newest team members!
  • Upcoming events our scientists will be attending or presenting at.
  • Publications and presentations by MetrumRG scientists.
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Topics: Metrum News

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