JAVELIN Recognition: Insights from One of the Most Cited Papers of the Year

Posted by Matthew Wiens, M.A. on Jun 5, 2024 10:36:10 AM

I am excited to share that one of our recent papers written in collaboration with EMD Serono, Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab, has been recognized as one of the most cited in its publication last year. Reflecting on this achievement, I wanted to provide some insights into why I believe this paper resonated so strongly with the pharmacometrics community and became such a valuable resource.

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Topics: Methodology, Tools, and Computation, Machine Learning, AI

Employee Spotlight: Kiersten Utsey

Posted by Barb Turney on May 3, 2024 4:25:51 PM

We're excited to shine the spotlight on Kiersten Utsey, a valued member of our team here at MetrumRG. Her primary focus involves utilizing mechanistic modeling and simulation to support decision-making processes throughout various stages of drug development. This entails synthesizing data from diverse sources, including in vitro studies, animal models, and clinical trials, to construct models that describe both the mechanism of action of drugs and the underlying physiology of diseases. Kiersten initially joined MetrumRG as a Quantitative Systems Pharmacology Intern while working on her Ph.D. in Mathematics at the University of Utah. After graduating from the U, Kiersten transitioned into a role as a research associate at MetrumRG. Quickly advancing, she became a research scientist in our Translational Science and Pharmacology (TSP) group. 

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Topics: Employee Spotlight

Celebrating 20 Years of Pursuing a Mission

Posted by Barb Turney on Mar 16, 2024 8:00:00 AM

Twenty years ago, the Metrum Research Group journey began. Marc Gastonguay and Jeff Hane founded the company in 2004 with a mission to improve health and defeat disease.

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Topics: Metrum News

Fostering Change: A Scientist's Path to Impact in Rare Disease Research

Posted by Megan Cala Pane on Feb 29, 2024 6:00:00 AM

I joined Metrum Research Group in the Fall of 2022 as a research scientist in PKPD, driven by a passion for modeling and simulation analyses of clinical trial data. My journey into this field was profoundly shaped by my experiences during a post-doc at a nonprofit organization, where I had the chance to collaborate closely with patient advocacy groups in the rare disease community. Their unwavering determination and resilience have inspired me to continue my work towards finding cures and creating innovative drug development solutions. In honor of Rare Disease Day, I am grateful to have the opportunity to share my journey of fruitful collaboration that has shaped my perspective.

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Employee Spotlight: Eric Anderson - Navigating Data with Dedication

Posted by Barb Turney on Feb 16, 2024 4:29:48 PM

Eric Anderson has been an invaluable member of the MetrumRG team since 2017. Over the years, has contributed a practical and dedicated approach to skillfully navigating the complexities of data.

Eric began his career in the insurance industry as an actuarial analyst. His experience in analyzing insurance data and modeling risk put him in a position to smoothly transition into the field of model-informed drug development at MetrumRG. In his current role, Eric assembles clinical trial data into model-ready datasets, creates visualizations (including interactive dashboards) to help describe data, and develops tools to help facilitate these and other modeling project tasks.

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Topics: Employee Spotlight

The Magic of Giving: A Look Back at How MetrumRG Spread Joy Through Our Annual Toy Drive

Posted by Barb Turney on Jan 2, 2024 5:50:30 PM

In the spirit of giving back, the MetrumRG team participated in an Annual Toy Drive benefiting Connecticut Children’s.  Over the years,  our team has made the holidays a little brighter by donating hundreds of toys to children throughout Connecticut, Eastern New York, and Western Massachusetts.

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Topics: Metrum News, Community Outreach

Employee Spotlight: Danielle Dunn - A Pillar of MetrumRG Since the Beginning

Posted by Barb Turney on Dec 14, 2023 7:00:00 AM

In this edition of our Employee Spotlight, we are delighted to introduce you to Danielle Dunn, one of the original team members at MetrumRG. Danielle's journey with the company has been one of unwavering dedication and commitment. For nearly two decades, she has been an integral part of our growth and success.

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Topics: Metrum News, Employee Spotlight

Metrum Research Group Announces Dr. Daniel Kirouac as Vice President of Translational and Systems Pharmacology

Posted by Barb Turney on Dec 12, 2023 8:00:00 AM

Metrum Research Group proudly welcomes Dr. Daniel Kirouac, Ph.D., as the Vice President of Translational and Systems Pharmacology (TSP). Dr. Kirouac brings over a decade of experience spanning academia, small biotech, big pharma, and consulting roles. His expertise in computational modeling and translational science will play a significant role in advancing drug development strategies at MetrumRG.

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Topics: Metrum News

Metrum Research Group Celebrates 13 years as a Marcum Tech Top 40 Company

Posted by Barb Turney on Oct 26, 2023 4:45:00 PM

Metrum Research Group has proudly earned a place on the Marcum Tech Top 40 list for the 13th year. At MetrumRG, we are passionate about our mission to defeat disease. We provide innovative solutions at the intersection of data, science, and technology to generate key insights that impact biomedical decision-making.

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Empowering Stories: A Personal Journey with Early-Stage Breast Cancer

Posted by Scotti Rylands on Oct 16, 2023 9:24:10 AM

In honor of Breast Cancer Awareness Month, I feel compelled to share my personal journey. Even though I'm not one to seek attention, this is a story that needs to be told.

Breast cancer has had a significant presence in my family's history. My mother, aunt, and cousin have all faced breast cancer, leading to mastectomies in their respective battles. Their experiences taught me an invaluable lesson: breast cancer awareness is not just about detecting lumps; it's about paying attention to any changes in your breasts – a message that applies to both women and men.

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Topics: Breast Cancer, Women's Health

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