News

Modeling methods for analyzing tumor dynamic data from basket trials

Posted by Alanna S. Ocampo-Pelland on Oct 18, 2017 9:01:02 AM

Poster presented by Alanna S. Ocampo-Pelland and Jonathan L. French at ACoP8. See the poster here

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Topics: Methodology, Tools, and Computation, Oncology, Open Science

Gaining Efficiency by Combining Analytical and Numerical Methods to Solve ODEs: Implementation in Stan and Application to Bayesian PK/PD Modeling

Posted by William R. Gillespie on Oct 17, 2017 9:30:12 AM
Poster presented at ACoP8 by  Charles C. Margossian  and William R. Gillespie. Check it out here
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Topics: Open Science

Slides available: Points to Consider when Making Inferences about Covariates

Posted by Marc Gastonguay on Oct 16, 2017 11:45:00 AM
Click here to access the slides from " Points to Consider when Making Inferences about Covariates" presented by Marc Gastonguay, Ph.D. at ACoP8 Session Quantification of Covariate Effects for Labeling. 
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Topics: Open Science

Theory, Empiricism, and a Vision for the Continued Growth of Pharmacometrics

Posted by Marc Gastonguay on Oct 15, 2017 11:17:16 PM

Slides Available: Dr. Marc Gastonguay's Sheiner Award lecture presented at ACoP8 on October 15, 2017. GastonguayISoPSheinerLecture2017final

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Topics: Open Science

An ODE to Open Science

Posted by Matthew M. Riggs, Ph.D. on Sep 29, 2017 8:05:00 AM

Developing quantitative systems pharmacology (QSP) models is hard work, without doubt. Such projects often take months, if not years, and may include extensive experimental contributions and input from numerous discipline experts.

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Topics: Open Science

Metrum Research Group Recipient of Marcum Tech Top 40 Award; Tenth Annual Event to Honor Metrum Research Group as one of 40 Fastest Growing Tech Companies

Posted by Michelle Johnson on Aug 26, 2017 8:01:30 AM

Tariffville, CT (August 25, 2017) - The Connecticut Technology Council (CTC) and Marcum LLP announced Metrum Research Group has made the Marcum Tech Top 40 (TT40) list of fastest growing technology companies in Connecticut. Metrum Research Group will be honored alongside 39 other TT40 companies at an awards ceremony on September 19th at the Oakdale Theatre in Wallingford. This marks the seventh time Metrum Research Group has been honored to be a Marcum Tech Top 40 recipient.

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Topics: Metrum News

Metrum Research Group Announces New President

Posted by Michelle Johnson on May 31, 2017 3:55:03 PM

Metrum Research Group is pleased to announce the appointment of Bill Knebel, Pharm.D., Ph.D. as President of the biomedical modeling and simulation services firm.

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Topics: Metrum News

Cloud Computing at ACoP

Posted by Tim Bergsma on May 31, 2017 3:54:23 PM

by Tim Bergsma

Already widely received in the finance community, cloud computing is gaining acceptance in the pharmaceutical industry as well. At this year’s American Conference on Pharmacometrics, Metrum Research Group staff presented a poster on the topic, and helped lead a related panel discussion.

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Topics: Methodology, Tools, and Computation

Alzheimer’s Association International Conference

Posted by Jim Rogers on May 31, 2017 3:53:20 PM

“Prevention … we have never uttered that word at the Alzheimer’s Association International Conference, and here we actually highlighted three clinical trials in the planning for prevention of Alzheimer’s … “. This comment from Dr. Mario Carrillo gives voice to the enthusiasm and interest of the attendees at the standing-room-only Alzheimer’s Association International Conference session entitled, “Collaboration for Alzheimer’s Prevention: Common Issues Across Presymptomatic Treatment Trials”, in which the A4, API, and DIAN prevention trials were discussed.

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Topics: Neurodegenerative Diseases

Adding Sinew to Roxygen Skeletons

Posted by Yoni Sidi on May 31, 2017 3:52:45 PM

For new developers, getting a package ready for building and submitting to CRAN is an expletive-filled, head-scratching experience to say the least. Trying to figure out the basics of what goes in depends and what goes in imports is a lost afternoon most of us would like back. Once that is understood, filling in relevant information to each field is a mundane task even for a well polished package developer. The out-of-the-box roxygen skeleton supplied by RStudio gives the bare bones road map of what should be part of function documentation:

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Topics: Methodology, Tools, and Computation