ISoP Regional QSP Day 2019

Posted by Marc Gastonguay on Jul 17, 2019 11:41:15 AM

Metrum Research Group scientists participated in the first International Society of Pharmacometrics (ISoP) Regional Quantitative Systems Pharmacology (QSP) Day on July 16, 2019. 

The meeting, which included podium presentations, a poster session, and opportunities for discussion and networking, highlighted several examples of the application of QSP methods in drug development. Particularly notable topics included: the integration of transcriptomics and systems pharmacology models, challenges with calibration of virtual patients in QSP models, and the use of QSP as a scaffold for bridging from well studied therapeutic indications to related but somewhat less understood indications.

Madeleine Gastonguay, of MetrumRG and University of Connecticut, presented the poster "Development of an open-source physiologically-based pharmacokinetic model to predict maternal-fetal exposures of CYP450-metabolized drugs". The open science philosophy, exemplified in this work, resonated with attendees and was also highlighted by several of the conference speakers.

Special thanks goes to the meeting organizers, the ISoP QSP Special Interest Group (ISoP QSP SIG), and hosts, Bristol-Myers Squibb (BMS), for a well organized event and an energizing, thought-provoking day.

Pictures from the event below.

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Topics: Methodology, Tools, and Computation, Open Science

MetrumRG Game Night Fundraiser for The Longest Day

Posted by Diane Reynolds on Jul 9, 2019 12:30:25 PM


Metrum Research Group staff and families recently participated the Alzheimer’s Association The Longest Day fundraiser. This initiative took place on June 21st, the summer solstice, the day with the most daylight. The goal of this day was to come together to fight the darkness of Alzheimer’s disease. Our employees participated in recognition of the many people we know who have been affected by this disease and also to acknowledge the contributions MetrumRG has made to help fight for a cure (some of this work can be seen here). Participants donated and joined in for a fun evening of playing games together. The game night theme symbolized the effort of keeping the brain active. The event resulted in a nice donation for the Alzheimer’s Association and a fun evening by all who attended.

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Topics: Community Outreach

MetrumRG Summer 2019 Newsletter

Posted by Shona Kidd on Jul 8, 2019 10:16:55 AM

Read the latest news, events, and publications from Metrum Research Group in our Summer 2019 Newsletter.

Here’s what you will find in our newsletter:  

  • MetrumRG now offers Clinical Pharmacology and Drug Development Strategy consulting services!
  • Find out more about our new team members!
  • A list of upcoming events our scientists will be attending or presenting at!
  • Publications and presentations by MetrumRG scientists!
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Topics: Metrum News

MetrumRG at PAGE 2019 Recap

Posted by Shona Kidd on Jun 17, 2019 3:00:00 PM

MetrumRG scientists traveled to Stockholm, Sweden to join the Population Approach Group in Europe for their 2019 annual meeting in June.

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Topics: Metrum News

Showing Stripes for Rare Disease Day

Posted by Diane Reynolds on Mar 7, 2019 12:17:00 PM

MetrumRG employees recognized Rare Disease Day on February 28th by participating in the National Organization for Rare Disorder’s Show Your Stripes campaign. While we work every day to develop therapies to fight disease, for the month of February we challenged employees and heightened awareness by highlighting different rare diseases in weekly meetings. On February 28th, we shared a pot luck lunch with a striped food theme and dressed to show off our stripes. MetrumRG employees across the country participated. We had a contest to see who had the best display of stripes and Metrum Research Group pledged a donation for each person that  participated in the stripes challenge. Check out the photos below of our day of recognition!

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Topics: Community Outreach

Rare Disease Day is February 28th

Posted by Diane Reynolds on Feb 15, 2019 8:39:51 AM

Metrum Research Group is raising awareness of Rare Disease Day during the entire month of February. Rare Disease Day occurs on February 28, 2019. The National Organization for Rare Disorders has issued a challenge to participate in recognizing rare diseases by showing your stripes, as the zebra is the official symbol of rare diseases in the United States. We have invited our employees to participate in a Show Your Stripes Challenge in the following ways:

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Topics: Community Outreach

Metrum Research Group February 2019 Newsletter

Posted by Diane Reynolds on Feb 14, 2019 9:18:48 AM

Click here to read the latest news from Metrum Research Group.

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Topics: Metrum News

Marc R. Gastonguay, Ph.D., awarded 2018 Bristol-Myers Squibb Mentorship in Clinical Pharmacology Award

Posted by Marc Gastonguay on Oct 10, 2018 3:59:21 PM

The following is a transcription of Dr. Gastonguay's acceptance speech when presented with the 2018 Bristol-Myers Squibb Mentorship in Clinical Pharmacology Award at the American College of Clinical Pharmacology on September 24, 2018.

Open Science: A Key to the Future Growth of Clinical Pharmacology.

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Topics: Open Science

Metrum Research Group Fall 2018 Newsletter

Posted by Shona Kidd on Oct 5, 2018 4:49:46 PM

Click here to read the latest news from Metrum Research Group!

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Topics: Metrum News

Metrum Research Group’s Leader of Statistical Modeling & Methods Promoted to Fellow

Posted by Diane Reynolds on Sep 6, 2018 8:27:49 AM

Metrum Research Group is pleased to announce the promotion of Jonathan French, D. Sci to Fellow

Tariffville, CT: Continuing the commitment to the scientific development of the Metrum Research Group (MetrumRG) team, Jonathan French, D. Sci. has been designated as Fellow within the Scientific Leadership Track. Dr. French also serves as Group Leader of the Statistical Modeling & Methods team at MetrumRG.

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Topics: Metrum News

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