A Significant Tilling of the Statistical Soil: The ASA Statement on Statistical Significance and P-values

Posted by Jim Rogers on Feb 7, 2020 10:01:59 AM

This is the first in a series of blog posts that will focus on practical problems of summarizing statistical evidence in the context of biomedical science, using the 2016 ASA statement on p-values and significance as a guide. I hope and expect that these posts will find a readership that does not entirely agree with my views in all of their particulars, and that this readership takes advantage of the blog / combox format to register both their agreements and disagreements. Merely good ideas are insufficient to the task at hand ; a shared understanding has to develop in the community of practice ; my hope here is to provide a forum for discussion for that community.

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Topics: Statistics, Scientific Writing, Significance, Confidence Intervals, P-values

Check out these recent publications by authors at Metrum Research Group and our collaborators!

Posted by Heidi Seaborg on Jan 16, 2020 8:00:00 AM


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Topics: Metrum News

MetrumRG Fall Community Outreach Efforts

Posted by Diane Reynolds on Dec 18, 2019 7:30:25 AM

The fall season brought several opportunities for MetrumRG employees to give to local communities.

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Topics: Community Outreach

MetrumRG at ACoP 2019

Posted by Diane Reynolds on Nov 19, 2019 12:58:45 PM

MetrumRG scientists traveled to Orlando, FL to join the American Conference on Pharmacometrics for their 2019 annual meeting in October.

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Topics: Metrum News

MetrumRG Fall 2019 Newsletter

Posted by Heidi Seaborg on Oct 2, 2019 1:28:51 PM


Read the latest news, events, and publications from Metrum Research Group in our Fall 2019 Newsletter.

Here’s what you will find in our newsletter:  

  • MetrumRG at ACoP10: Our workshops, presentations, and posters!
  • Announcement about our newest team members!
  • Upcoming events our scientists will be attending or presenting at.
  • Publications and presentations by MetrumRG scientists.
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Topics: Metrum News

MetrumRG at Walk MS

Posted by Diane Reynolds on Sep 20, 2019 11:20:56 AM


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Topics: Community Outreach

Proposal for an Open Software Development Life Cycle

Posted by Marc Gastonguay on Sep 16, 2019 2:31:04 PM

The confluence of several factors, including: the growing recognition of the value of quantitative approaches to decision-making in drug development, advancements in numerical methods and analytics, and democratization of modern software engineering, has led to the emergence of multiple pharmacometrics-related software tools, both commercially and publicly licensed. A rigorously managed, high-quality, software development practice is central to reliable and reproducible scientific application and regulatory compliance for these tools. Professional software development best practices should typically be outlined in a Software Development Life Cycle (SDLC) policy or procedure, but the extent of guidance, consistency of methods, adherence to procedures, completeness of quality documentation, and execution rigor vary greatly across software development organizations or teams.

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Topics: Methodology, Tools, and Computation, Open Science

MetrumRG at R/Pharma

Posted by Michelle Johnson on Aug 28, 2019 4:08:50 PM

August 21-23, 2019

MetrumRG scientists visited Harvard University to participate in the R/Pharma conference.

This was the second annual R/Pharma conference, which included keynotes from renowned industry practitioners, key R developers, and leading academics. There were also several full-length presentations as well as a number of shorter, highly-energetic lightning talks. And new this year, pre-conference workshops were offered to the 150 attendees. MetrumRG was honored to deliver three presentations and to support the event again this year by hosting a mixer on Thursday night. Congratulations to the organizing committee for another successful R/Pharma!

Here is a recap of our MetrumRG presentations:

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Where to find MetrumRG in August!

Posted by Shona Kidd on Aug 12, 2019 8:09:18 AM

Our scientists are attending and presenting at many conferences in August. Here's where you can find them:

Read on for more information:

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Topics: Metrum News

MetrumRG at JSM2019 in Denver, CO

Posted by Shona Kidd on Aug 2, 2019 1:55:53 PM

MetrumRG scientists attended and presented at the 2019 Joint Statistical Meetings (JSM) in Denver, CO. JSM is renowned as the largest gathering of statisticians and data scientists held in North America.

On Thursday, Michael Heathman, M.S., presented "Integration of Pharmacometrics and Statistics to Support Study Design Optimization".

For more pictures, read on!
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Topics: Metrum News

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